125986-52-9Relevant academic research and scientific papers
THE MICHAEL ADDITION OF ENAMINES TO PROPENAMIDINES. A CONVENIENT SYNTHESIS OF 2-β-AMIDINOETHYLCYCLOALKANONES BY AMIDINOETHYLATION REACTION
Fuks, Robert,Bril, Marc Van den
, p. 1681 - 1696 (2007/10/02)
A variety of propenamidines 3 have been reacted with enamines of cyclopentanone and cyclohexanone giving after hydrolysis of the Stork enamine 6, 2-β-amidinoethylcyclopentanones 8 and -hexanones 7.This reaction illustrates the electrophilic character of the C=C double bond due to the conjugated amidine function, thus providing with propenamidines 3 a new class of Michael acceptors for enamines.
