1259945-99-7

Basic information

• Product Name: N-{4-[5-(2-thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile
• CAS NO: 1259945-99-7
• Molecular Weight: 423.495
• Mol File: 1259945-99-7.mol

Chemical Properties

• CAS DataBase Reference: N-{4-[5-(2-thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-[5-(2-thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile(1259945-99-7)
• EPA Substance Registry System: N-{4-[5-(2-thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile(1259945-99-7)

Safety Data

• Hazardous Substances Data: 1259945-99-7(Hazardous Substances Data)

Upstream product

• 55696-50-9 tert-butyl 4-cyanobenzoate 
• 338972-00-2 Boc-Leu-Cl 
• 6068-72-0 4-cyanobenzoyl chlorIde 
• 619-65-8 4-cyanobenzoic Acid 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 1259946-99-0 4-[5-(thiophen-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid 
• 1259946-96-7 4-[(2-thiophenecarbonyl)oxyamidino]benzoic acid tert-butyl ester 
• 5105-64-6 (S)-2-amino-N-(cyanomethyl)-4-methylpentanamide 
• 184576-27-0 C₁₂H₁₆N₂O₃ 

Relevant articles and documents

Structural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors

Using the example of cathepsin K, we demonstrate the design of highly potent and selective azadipeptide nitrile inhibitors. A systematic scan with respect to P2 and P3 substituents was carried out. Structural modifications strongly affected the enzyme-inh