125995-17-7 Usage
Description
(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid is a complex organic compound with a unique molecular structure. It is characterized by its chiral centers at the 4R and 6R positions, as well as its 1,3-dioxane ring and aminoethyl side chain. (4R,6R)-6-(2-AMinoethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid is known for its role as a key intermediate in the synthesis of Atorvastatin, a widely prescribed medication for lowering cholesterol levels.
Uses
Used in Pharmaceutical Industry:
(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid is used as an intermediate in the synthesis of Atorvastatin (A791750) for the treatment of hypercholesterolemia. It plays a crucial role in the production of this cholesterol-lowering drug, which helps to reduce the risk of cardiovascular diseases by managing lipid levels in the blood.
Check Digit Verification of cas no
The CAS Registry Mumber 125995-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,9,9 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125995-17:
(8*1)+(7*2)+(6*5)+(5*9)+(4*9)+(3*5)+(2*1)+(1*7)=157
157 % 10 = 7
So 125995-17-7 is a valid CAS Registry Number.
125995-17-7Relevant articles and documents
Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
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, (2008/06/13)
An improved process for the preparation of trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-ones by a novel synthesis is described where 1,6-heptadien-4-ol is converted in eight operations to the desired products, as well as an improved process for the preparation of (2R-trans) and trans-(±)-5-(4-fluorophenyl)-2-(1-methylethyl)-N-4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1H-pyrrole-3-carboxamide by a novel synthesis where 4-methyl-3-oxo-N-phenylpentanamide is converted in eight operations to the desired product or alternatively 4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzenebutaneamide is converted in one step to the desired product, and additionally, a process for preparing (2R-trans)-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1H-pyrrole-3-carboxamide from (R)-4-cyano-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]butanoic acid, as well as other valuable intermediates used in the processes.
