125996-71-6 Usage
Description
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE is a chemical compound characterized by a molecular structure that features a pyridine ring linked to a trifluoromethyl-phenyl group through a ketone functional group. 2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE is known for its aromatic and carbonyl functional groups, which enable it to engage in a broad spectrum of chemical reactions. Its molecular composition, including the pyridine moiety—a prevalent structural element in numerous pharmaceutical agents—and the trifluoromethyl substituent, suggests potential applications in medicinal and biological chemistry, with the latter potentially enhancing biological activity and chemical stability.
Uses
Used in Pharmaceutical Synthesis:
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE is utilized as an intermediate in the synthesis of various pharmaceuticals, leveraging its versatile chemical reactivity and structural features to contribute to the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE serves as an intermediate, playing a crucial role in the creation of compounds designed to protect crops and enhance agricultural productivity.
Used in Medicinal Chemistry Research:
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE is employed as a research compound in medicinal chemistry, where its pyridine ring and trifluoromethyl group are studied for their potential to improve the efficacy and stability of drug candidates.
Used in Biological Chemistry Applications:
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE is also used in biological chemistry for exploring its interactions with biological systems, potentially leading to the discovery of new bioactive molecules or insights into biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 125996-71-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,9,9 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 125996-71:
(8*1)+(7*2)+(6*5)+(5*9)+(4*9)+(3*6)+(2*7)+(1*1)=166
166 % 10 = 6
So 125996-71-6 is a valid CAS Registry Number.
125996-71-6Relevant articles and documents
THERAPEUTIC METHODS AND COMPOUNDS
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Page/Page column 20-22; 69, (2020/11/03)
The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.
Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase
Walker, John K.,Selness, Shaun R.,Devraj, Rajesh V.,Hepperle, Michael E.,Naing, Win,Shieh, Huey,Kurambail, Ravi,Yang, Syaulan,Flynn, Daniel L.,Benson, Alan G.,Messing, Dean M.,Dice, Tom,Kim, Tina,Lindmark,Monahan, Joseph B.,Portanova, Joseph
scheme or table, p. 2634 - 2638 (2010/07/13)
Starting from an initial HTS screening lead, a novel series of C(5)-substituted diaryl pyrazoles were developed that showed potent inhibition of p38α kinase. Key to this outcome was the switch from a pyridyl to pyrimidine at the C(4)-position leading to analogs that were potent in human whole blood based cell assay as well as in a number of animal efficacy models for rheumatoid arthritis. Ultimately, we identified a clinical candidate from this substrate; SD-0006.
Adenosine A3 receptor antagonists
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, (2008/06/13)
A pharmaceutical composition for antagonizing adenosine at adenosine A3receptors which comprises a 1,3-azole compound substituted on the 4- or 5-position, or both, by a pyridyl which may be substituted is provided and can be used as a prophylactic and therapeutic agent for asthma, allergosis, inflammation, and so on.