1260002-07-0Relevant articles and documents
Click-based synthesis and proteomic profiling of lipstatin analogues
Ngai, Mun H.,Yang, Peng-Yu,Liu, Kai,Shen, Yuan,Wenk, Markus R.,Yao, Shao Q.,Lear, Martin J.
supporting information; experimental part, p. 8335 - 8337 (2010/12/25)
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved