126005-06-9Relevant academic research and scientific papers
Sequential Michael Addition and Enamine-Promoted Inverse Electron Demanding Diels-Alder Reaction upon 3-Vinyl-1,2,4-triazine Platforms
Lorion, Magali,Guillaumet, Gérald,Brière, Jean-Fran?ois,Suzenet, Franck
, p. 3154 - 3157 (2015/06/30)
An original one-pot Michael addition-ihDA/rDA sequence was achieved from 3-vinyl-1,2,4-triazine platforms used as unprecedented Michael acceptors. This sequence provides a novel access to functionalized [2,3]-fused pyridine derivatives via a unique enamin
Ti(OiPr)4/nBuLi: An attractive reagent system for [2+2+2] cyclotrimerisation reactions
Rassadin,Nicolas,Six
supporting information, p. 7666 - 7669 (2014/07/08)
A convenient method for the [2+2+2] cyclotrimerisation of alkynes using Ti(OiPr)4/nBuLi is presented. Homotrimerisation of arylacetylenes proceeds within minutes with excellent regioselectivity. Moreover, the intermolecular construction of ABB heterotrimers can be achieved selectively from two different alkynes with similar electronic properties. The method is also suitable for the synthesis of pyridines.
Intramolecular Diels-Alder Reactions of 1,2,4-Triazines. Synthesis of 2,3-Cyclopentenopyridines and 5,6,7,8-Tetrahydroquinolines
Taylor, Edward C.,Macor, John E.,French, Larry G.
, p. 1807 - 1812 (2007/10/02)
2,3-Cyclopentenopyridines and 5,6,7,8-tetrahydroquinolines are prepared by intramolecular Diels-Alder reactions of appropriately substituted 1,2,4-triazines.Two general routes to the requisite triazine precursors are described.
