77758-51-1

Basic information

• Product Name: METHYL 5-HEXYNOATE
• Synonyms: METHYL 5-HEXYNOATE;TIMTEC-BB SBB009076;Methyl 5-hexynoate,95%;Methyl 5-hexynote;Methyl 5-hexynoate, 95% 5GR;Methyl hex-5-ynoate
• CAS NO: 77758-51-1
• Molecular Formula: C₇H₁₀O₂
• Molecular Weight: 126.15
• Mol File: 77758-51-1.mol
• Article Data: 34

Chemical Properties

• Boiling Point: 60 °C
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 0.960±0.06 g/cm3(Predicted)
• Refractive Index: 1.434
• CAS DataBase Reference: METHYL 5-HEXYNOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-HEXYNOATE(77758-51-1)
• EPA Substance Registry System: METHYL 5-HEXYNOATE(77758-51-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-52
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 77758-51-1(Hazardous Substances Data)

Usage

Description

METHYL 5-HEXYNOATE is a clear colorless to pale yellow liquid that is utilized in various chemical reactions and synthesis processes. It is an organic compound with the potential for further modification and application in different industries.

Uses

Used in Chemical Synthesis:
METHYL 5-HEXYNOATE is used as a chemical intermediate for the synthesis of methyl (Z)-8-chlorooct-7-ene-5-ynoate with (Z)-1,2-dichloro-ethane. This application takes advantage of its reactivity and ability to form new compounds with desired properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, METHYL 5-HEXYNOATE may be used as a starting material or intermediate in the development of new drugs or drug candidates. Its chemical properties make it a versatile compound for further modification and exploration in medicinal chemistry.
Used in Flavor and Fragrance Industry:
Given its status as an organic compound, METHYL 5-HEXYNOATE could potentially be used in the flavor and fragrance industry to create unique scents or enhance existing ones. Its clear colorless to pale yellow liquid form may also make it suitable for use in products where color is a consideration.
Used in Research and Development:
METHYL 5-HEXYNOATE can be employed in research and development settings to study its properties, reactivity, and potential applications in various fields. This may include exploring its use in materials science, environmental applications, or other emerging technologies.

Upstream product

• 67-56-1 methanol 
• 53293-00-8 hex-5-ynoic acid 
• 77-76-9 2,2-dimethoxy-propane 
• 108545-38-6 5-hexynoic acid ethyl ester 
• 2468-55-5 5-iodopent-1-yne 
• 14267-92-6 1-chloro-4-pentyne 
• 14918-21-9 5-hexynonitrile 
• 108545-33-1 6-(2-Nitro-phenylselanyl)-hexanoic acid methyl ester 
• 14273-90-6 methyl 6-bromohexanoate 
• 100-72-1 Tetrahydropyran-2-methanol 
• 18420-41-2 2-(chloromethyl)tetrahydropyran 
• 928-90-5 5-hexyl-1-ol 
• 764-60-3 hex-2-yn-1-ol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 111770-83-3 methyl6-(5-bromo-2-pyridinyl)-5-hexynoate 
• 928-90-5 5-hexyl-1-ol 
• 53293-00-8 hex-5-ynoic acid 
• 158780-93-9 4-(methyl-1-pentynoate)-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 164409-73-8 6-(2-Bromo-phenyl)-hex-5-ynoic acid methyl ester 
• 108545-38-6 5-hexynoic acid ethyl ester 
• 1055873-72-7 (E)-9,9-diphenyl-9-(trimethylsilanyloxy)non-5-en-7-ynoic acid methyl ester 
• 1097645-26-5 methyl 6-(4,5-dimethyl-2-(3-oxopentyl)phenyl)hex-5-ynoate 
• 1314185-58-4 methyl (Z)-5-chloro-7,8-dioxo-8-phenyl-5-octenoate 
• 1616967-52-2 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one 
• 478688-31-2 methyl rac-(5Z,8Z,11Z,14Z)-18-(benzoyloxy)eicosa-5,8,11,14-tetraenoate 
• 914257-32-2 6-(3-bromo-phenyl)-hex-5-ynoic acid methyl ester 
• 896101-39-6 6-(2-methylcarbamoylmethyl-phenyl)-hex-5-ynoic acid methyl ester 
• 28093-53-0 methyl 4-(1H-indol-2-yl)butanoate 

Relevant articles and documents

Synthesis of a Tyr3-octreotate conjugated closo-carborane [HC2B10H10]: a potential compound for boron neutron capture therapy

A novel Tyr3-octreotate conjugated closo-carborane as a potential compound for boron neutron capture therapy was obtained via Fmoc solid phase peptide synthesis. The boron cluster [C2B10H11] was introduced through the reaction of 6,9-bi(acetonitrile)decaborane and 5-hexynoic acid yielding a new closo-carborane conjugated carboxylic acid which was coupled subsequently with solid phase conjugated Tyr3-octreotate. The final boron-containing peptide was purified by preparative reverse phase HPLC and structural identity was proved applying MALDI-TOF mass spectrometry.

Gold-catalyzed Rapid Construction of Nitrogen-containing Heterocyclic Compound Library with Scaffold Diversity and Molecular Complexity

1,3-unsubstituted 2-(1H-indol-2-yl)ethanamines were employed for the first time to react with alkynoic acids (AAs) to achieve gold-catalyzed highly selective cascade reactions to furnish novel indole-fused skeletons. Furthermore, with this powerful gold catalytic system, a library of indole/pyrrole/thiophene/benzene/naphthalene/pyridine-based nitrogen-containing heterocyclic compounds (NCHCs) with scaffold diversity and molecular complexity was constructed rapidly using various amine nucleophiles (ANs) and diverse AAs as the building blocks. This general protocol features excellent selectivity, extraordinarily broad substrate scope, readily available inputs, good to high yields, high bond-forming efficiency, and step economy, thus providing a facile and efficient access to a variety of valuable nitrogen-containing heterocycles.

Single-Molecule Observation of the Intermediates in a Catalytic Cycle

The development of catalysts benefits from knowledge of the intermediate steps that accelerate the transformations of substrates into products. However, key transient species are often hidden in ensemble measurements. Here, we show that a protein nanoreac