1260073-32-2Relevant articles and documents
Pyrimidinylmethylphenyl glucoside as novel C-aryl glucoside SGLT2 inhibitors
Lee, Junwon,Kim, Jong Yup,Choi, Jungsub,Lee, Sung-Han,Kim, Jeongmin,Lee, Jinhwa
experimental part, p. 7046 - 7049 (2010/12/25)
Novel C-aryl glucoside SGLT2 inhibitors containing pyrimidine motif were designed and synthesized for biological evaluation. Among the compounds assayed, pyrimidine containing methylthio moiety 11g demonstrated the best in vitro inhibitory activity against SGLT2 in this series to date (IC50 = 10.7 nM).