126008-80-8

Upstream product

• 51334-86-2 4-(4-chlorophenyl)-1-(2H)-phthalazinone 
• 85-56-3 2-(4-chlorobenzoyl)benzoic acid 
• 40848-52-0 1-chloro-4-(4-chlorophenyl)-phthalazine 

Downstream Products

• 126008-83-1 N-[4-(4-Chloro-phenyl)-phthalazin-1-yl]-N'-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-hydrazine 
• 126008-91-1 6-(4-Chloro-phenyl)-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine 
• 126008-93-3 6-(4-Chloro-phenyl)-3-(3,4-dimethoxy-phenyl)-[1,2,4]triazolo[3,4-a]phthalazine 
• 126008-95-5 6-(4-Chloro-phenyl)-3-(2-nitro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazine 
• 126008-92-2 6-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-[1,2,4]triazolo[3,4-a]phthalazine 
• 126008-94-4 6-(4-Chloro-phenyl)-3-p-tolyl-[1,2,4]triazolo[3,4-a]phthalazine 
• 126008-85-3 N-[4-(4-Chloro-phenyl)-phthalazin-1-yl]-N'-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-hydrazine 
• 126008-82-0 N-[4-(4-Chloro-phenyl)-phthalazin-1-yl]-N'-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazine 
• 126008-81-9 N-[4-(4-Chloro-phenyl)-phthalazin-1-yl]-N'-[1-phenyl-meth-(Z)-ylidene]-hydrazine 
• 126008-84-2 N-[4-(4-Chloro-phenyl)-phthalazin-1-yl]-N'-[1-p-tolyl-meth-(Z)-ylidene]-hydrazine 

Relevant academic research and scientific papers

Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

Treatment of patients with triple-negative breast cancer (TNBC) is challenging due to the absence of well- defined molecular targets and the heterogeneity of such disease. In our endeavor to develop potent isatin-based anti-proliferative agents, we utiliz

Synthesis and biological activity of 3,6-diaryl-1,2,4-triazolo-phthalazines

4-(4'-Chlorophenyl)-1-hydrazinophthalazine (1) and 4-(4'-methoxyphenyl)-1-hydrazinophthalazine (2) condense with aromatic aldehydes (3) to give 4-(4'-chlorophenyl)-1-benzalhydrazinonaphthalazines (4) and 4-(4'-methoxyphenyl)-1-benzalhydrazinonaphthalazine