1260181-11-0

Basic information

• Product Name: 3-(5-dimethylamino-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione
• CAS NO: 1260181-11-0
• Molecular Weight: 399.372
• Mol File: 1260181-11-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(5-dimethylamino-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-dimethylamino-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione(1260181-11-0)
• EPA Substance Registry System: 3-(5-dimethylamino-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione(1260181-11-0)

Safety Data

• Hazardous Substances Data: 1260181-11-0(Hazardous Substances Data)

Upstream product

• 1260181-07-4 3-(5-fluoro-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 
• 124-40-3 dimethyl amine 
• 1260181-08-5 2-(5-fluoro-2-(trifluoromethyl)phenyl)acetamide 
• 239135-52-5 2-(5-fluoro-2-(trifluoromethyl)phenyl)acetic acid 

Relevant articles and documents

Identification of a potent janus kinase 3 inhibitor with high selectivity within the janus kinase family

We describe a synthetic approach toward the rapid modification of phenyl-indolyl maleimides and the discovery of potent Jak3 inhibitor 1 with high selectivity within the Jak kinase family. We provide a rationale for this unprecedented selectivity based on