126027-83-6

Upstream product

• 126027-82-5 (4S,5S)-5-((R)-3-tert-Butoxy-2-methyl-propyl)-4-cyclohexylmethyl-oxazolidin-2-one 
• 147426-18-4 (R)-3-((4S,5S)-4-Cyclohexylmethyl-2-oxo-oxazolidin-5-yl)-2-methyl-propionic acid 
• 117760-77-7 ((1S,2S,4R)-5-tert-Butoxy-1-cyclohexylmethyl-2-hydroxy-4-methyl-pentyl)-carbamic acid tert-butyl ester 
• 126107-72-0 ((1S,2R,4R)-5-tert-Butoxy-1-cyclohexylmethyl-2-hydroxy-4-methyl-pentyl)-carbamic acid tert-butyl ester 
• 98105-42-1 (S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-1-propanal 
• 147426-12-8 (2R,4S,5S)-5-<(tert-butyloxycarbonyl)amino>-6-cyclohexyl-4-hydroxy-2-phenylhexane 
• 147426-13-9 (4S,5S)-4-Cyclohexylmethyl-5-((R)-2-phenyl-propyl)-oxazolidin-2-one 

Downstream Products

• 117760-82-4 (4S,5S)-4-Cyclohexylmethyl-5-[(R)-2-methyl-3-(propane-2-sulfonyl)-propyl]-oxazolidin-2-one 
• 117760-83-5 (2S,3S,5R)-2-Amino-1-cyclohexyl-5-methyl-6-(propane-2-sulfonyl)-hexan-3-ol 
• 126027-84-7 (4S,5S)-4-Cyclohexylmethyl-5-((R)-3-isopropylsulfanyl-2-methyl-propyl)-oxazolidin-2-one 

Relevant academic research and scientific papers

A Short Stereocontrolled Synthesis of Hydroxyethylene Dipeptide Isosteres

A stereocontrolled synthesis of protected hydroxyethylene dipeptide isosteres 14 and 16 is described.It provides the 2R,4S,5S epimers required for the preparation of aspartic proteinase inhibitors.The choice of a benzene ring as a precursor to the carboxy

SYNTHESIS OF A NEW SULFUR-CONTAINING DIPEPTIDE ANALOGUE

The synthesis of a sulfur-containing Cha-Ala isostere is reported (Cha=cyclohexylalanine).The diastereoconversion of a N-2-Boc-amino alcohol has been achieved by treatment with methanesulfonyl chloride in pyridine resulting in the corresponding oxazolidin