126027-99-4

Upstream product

• 2280-66-2 N-tert-butyloxycarbonylalanylphenylalanine methyl ester 

Downstream Products

• 128421-91-0 Boc-Ala-ψ(CH2NH)-Phe-OMe 
• 107254-14-8 (S)-2-((S)-2-Amino-thiopropionylamino)-3-phenyl-propionic acid methyl ester 
• 142765-15-9 Boc-D-AlaΨPhe-Leu-NH2 
• 142765-13-7 N-tert-Butyloxycarbonyl-D-thioalanyl-L-phenylalanyl-L-valinallylester 
• 142765-21-7 Boc-D-AlaΨPhe-Val-Lys(Z)-Trp-Phe-OMe 
• 142765-22-8 H-D-AlaΨPhe-Val-Lys(Z)-Trp-Phe-OH 
• 206123-99-1 (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-thiopropionylamino]-3-phenyl-propionic acid methyl ester 

Relevant academic research and scientific papers

Modulation of the peptide backbone conformation by the selenoxo photoswitch

Photocontrol of the backbone conformation is a useful step forward in regulating the bioactivities of peptides and proteins by means of external signals. In the present work, the selenium analogue of a peptide bond was introduced into tetrapeptides to obt

Endothiopeptide inhibitors of HIV-1 protease

Endothiopeptide inhibitors of HIV-1 protease were synthesized by chemical and enzymatic methods to individually replace each backbone amide bond in 1 with a thioamide-linkage. Interestingly, agent 7, which contains a thioamide-linkage between the P2

Synthesis and Reactions of Endothiopeptides

Direct replacement of oxygen by sulphur in a peptide bond results in an endothiopeptide.This replacement can be accomplished by use of Lawesson's reagent 1; however, significant limitations are associated with this method.An improved procedure for the dir