1260389-55-6Relevant articles and documents
Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity
Woo, L. W. Lawrence,Bubert, Christian,Purohit, Atul,Potter, Barry V. L.
scheme or table, p. 243 - 247 (2011/04/25)
Single agents against multiple drug targets are highly topical. Hormone-dependent breast cancer (HDBC) may be more effectively treated by dual inhibition of aromatase and steroid sulfatase (STS), and several dual aromatase-sulfatase inhibitors (DASIs) hav