1260422-99-8 Usage
Description
Tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate is a chemical compound characterized by its molecular formula C11H21NO2. It is a derivative of diazepane, featuring a seven-membered ring with two nitrogen atoms. tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate's structure is distinguished by the presence of a tert-butyl group and a methyl group, which confer a branched and bulky nature. tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate is valued for its stable and sterically hindered properties, making it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
Tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate is utilized as a key building block in the synthesis of various drugs. Its unique structure and properties allow for the creation of complex molecules that can be tailored for specific therapeutic applications.
Used in Organic Synthesis:
In the realm of organic synthesis, Tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate serves as a valuable reagent. Its stable and sterically hindered nature makes it suitable for use in a wide range of chemical reactions, contributing to the development of novel compounds and materials.
Used in Creation of Complex Molecules:
tert-Butyl 2-Methyl-1,4-diazepane-1-carboxylate is also employed in the design and synthesis of complex molecules, where its structural features can be leveraged to achieve specific chemical and biological properties. This application is particularly relevant in the development of new pharmaceuticals and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1260422-99-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,4,2 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1260422-99:
(9*1)+(8*2)+(7*6)+(6*0)+(5*4)+(4*2)+(3*2)+(2*9)+(1*9)=128
128 % 10 = 8
So 1260422-99-8 is a valid CAS Registry Number.
1260422-99-8Relevant articles and documents
A practical synthesis of (S)- tert -butyl 3-methyl-1,4-diazepane-1- carboxylate, the key intermediate of rho-kinase inhibitor K-115
Gomi, Noriaki,Kouketsu, Akiyasu,Ohgiya, Tadaaki,Shibuya, Kimiyuki
, p. 3171 - 3178 (2012/11/14)
A practical synthesis of (S)-tert-butyl 3-methyl-1,4-diazepane-1- carboxylate has been established for supplying this key intermediate of Rho-kinase inhibitor K-115 in a multikilogram production. The chiral 1,4-diazepane was constructed by intramolecular Fukuyama-Mitsunobu cyclization of a N-nosyl diamino alcohol starting from the commercially available (S)- or (R)-2-aminopropan-1-ol. In the same manner, an enantiomeric pair of a structural isomer were prepared for demonstration of the synthetic utility.
