126045-22-5Relevant academic research and scientific papers
REACTION OF α, β, α', β'-DIEPOXYKETONES WITH METHANOL IN THE PRESENCE OF BORON TRIFLUORIDE ETHERATE
Zvonok, A. M.,Kuz'menok, N. M.,Stanishevskii, L. S.
, p. 978 - 983 (2007/10/02)
The reaction of trans-diepoxyketones with methanol in the presence of boron trifluoride etherate leads to tetrahydropyran-4-ones and/or tetrahydrofuran-3-ones.The size of the heterocycle forming depends on the direction in which the alkylsubstituted epoxide ring opens and is determined by the relative configuration of the chiral centers of the epoxide rings.
