126052-34-4

Basic information

• Product Name: 3-phenylimidazo[1,2-a]pyrazine
• Synonyms: 3-phenylimidazo[1,2-a]pyrazine;IMidazo[1,2-a]pyrazine, 2-phenyl-;2-PhenyliMidazo[1,2-a]pyrazine
• CAS NO: 126052-34-4
• Molecular Formula: C₁₂H₉N₃
• Molecular Weight: 195
• Mol File: 126052-34-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 132-134℃
• Appearance: /
• Density: 1.21g/cm³
• Refractive Index: 1.674
• Storage Temp.: 2-8°C
• PKA: 3.48±0.30(Predicted)
• CAS DataBase Reference: 3-phenylimidazo[1,2-a]pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylimidazo[1,2-a]pyrazine(126052-34-4)
• EPA Substance Registry System: 3-phenylimidazo[1,2-a]pyrazine(126052-34-4)

Safety Data

• Hazardous Substances Data: 126052-34-4(Hazardous Substances Data)

Usage

General Description

3-Phenylimidazo[1,2-a]pyrazine is a chemical compound with the molecular formula C10H7N3. It is a heterocyclic compound that contains a pyrazine ring and an imidazole ring fused together with a phenyl group attached to the nitrogen atom. 3-Phenylimidazo[1,2-a]pyrazine has potential applications in the field of medicinal chemistry and drug discovery due to its unique structure and biological activities. It has been studied for its potential as an anti-cancer agent and as a scaffold for the development of new pharmaceutical compounds. Additionally, 3-Phenylimidazo[1,2-a]pyrazine has been investigated for its potential as a fluorescent probe for detecting metal ions in biological systems. Further research is needed to fully understand the properties and potential applications of this chemical compound.

InChI:InChI=1/C12H9N3/c1-2-4-10(5-3-1)11-9-15-7-6-13-8-12(15)14-11/h1-9H

Upstream product

• 1447607-84-2 8-chloro-2-phenylimidazo[1,2-a]pyrazine 
• 98-86-2 acetophenone 
• 5049-61-6 2-Aminopyrazine 
• 98-80-6 phenylboronic acid 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 1254709-40-4 3-bromo-2-phenylimidazo[1,2-a]pyrazine 

Relevant articles and documents

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

A series of original 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyrazines and the 3-iodo precursors, bearing a polar moiety at the C-8 position, was synthesized and evaluated for their antileishmanial activities. Two derivatives exhibited very good activity a

IMIDAZOPYRAZINES AND PYRAZOLOPYRIMIDINES AND THEIR USE AS AMPA RECEPTOR MODULATORS

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, N-oxides, or solvates thereof, [Formula should be inserted here] Also provided herein are pharmaceutical compositions, comprising compounds of Formula (I), and methods of

Structure activity relationship studies of imidazo[1,2-a]pyrazine derivatives against cancer cell lines

Designed novel imidazo[1,2-a]pyrazine based inhibitors, synthesized by condensing α-aminopyrazines with α-halocarbonyl compounds followed by electrophilic substitutions. Cytotoxic effects on four cancer cell lines evaluated. Based on preliminary data, imidazo[1,2-a]pyrazine template redesigned to improve activity.