1260586-85-3Relevant academic research and scientific papers
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity
Umeda, Nobuhiro,Ueno, Tasuku,Pohlmeyer, Christopher,Nagano, Tetsuo,Inoue, Takanari
, p. 12 - 14 (2011)
We developed a novel method to spatiotemporally control the activity of signaling molecules. A newly synthesized photocaged rapamycin derivative induced rapid dimerization of FKBP (FK-506 binding protein) and FRB (FKBP-rapamycin binding protein) upon UV i
