1261268-94-3 Usage
Uses
Used in Pharmaceutical Synthesis:
Ethyl 4-(5-Oxazolyl)benzoate is used as an intermediate in the production of various drugs. Its unique structure allows for versatile reactivity, making it a valuable component in the synthesis of a range of pharmaceutical compounds.
Used in Agrochemical Production:
In the agrochemical industry, Ethyl 4-(5-Oxazolyl)benzoate is utilized as a key intermediate for the synthesis of various agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Organic Synthesis:
Ethyl 4-(5-Oxazolyl)benzoate is used as a versatile reagent in organic synthesis, taking advantage of its benzoate ester group and oxazole ring to facilitate a variety of chemical reactions, leading to the creation of diverse organic compounds.
Used in Fine Chemicals Production:
Ethyl 4-(5-Oxazolyl)benzoate is also used in the production of fine chemicals, where its specific reactivity and structural features are leveraged to produce high-quality specialty chemicals for various applications.
Used in Medical Research:
Ethyl 4-(5-Oxazolyl)benzoate is used in research for its potential pharmacological properties, with ongoing investigations into its use in the treatment of various medical conditions, highlighting its potential as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 1261268-94-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,2,6 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1261268-94:
(9*1)+(8*2)+(7*6)+(6*1)+(5*2)+(4*6)+(3*8)+(2*9)+(1*4)=153
153 % 10 = 3
So 1261268-94-3 is a valid CAS Registry Number.
1261268-94-3Relevant academic research and scientific papers
Shi, Xinzhe,Soulé, Jean-Fran?ois,Doucet, Henri
, p. 4748 - 4760 (2019)
Two sets of reaction conditions for the regiodivergent C2- or C5- direct arylations of oxazole are reported. In both cases, phosphine-free catalysts and inexpensive bases were employed allowing the access to the arylated oxazoles in moderate to high yields. Using Pd(OAc)2/KOAc as catalyst and base, regioselective C5-arylations were observed; whereas, using Pd(acac)2/Cs2CO3 system, the arylation occurred at the C2-position of oxazole. The higher reactivity of C5-H bond of oxazole as compared to the C2-H bond in the presence of Pd(OAc)2/KOAc system is consistent with a concerted metalation deprotonation mechanism; whereas the C2-arylation likely occurs via a simple base deprotonation of the oxazole C2-position. Then, from these C2- or C5-arylated oxazoles, a second palladium-catalyzed direct C?H bond arylation affords 2,5-diaryloxazoles with two different aryl groups. We also applied these sequential arylations to the straightforward synthesis of 2-arylphenanthro[9,10-d]oxazoles via three C?H bond functionalization steps. The Ru-catalyzed C?H arylation of the aryl unit of 2-aryloxazoles is also described. (Figure presented.).
