126135-40-8

Basic information

• Product Name: methyl 4-hydroxy-4-(4-bromophenyl)butanoate
• Synonyms: methyl 4-hydroxy-4-(4-bromophenyl)butanoate
• CAS NO: 126135-40-8
• Molecular Weight: 273.126
• Mol File: 126135-40-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl 4-hydroxy-4-(4-bromophenyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-hydroxy-4-(4-bromophenyl)butanoate(126135-40-8)
• EPA Substance Registry System: methyl 4-hydroxy-4-(4-bromophenyl)butanoate(126135-40-8)

Safety Data

• Hazardous Substances Data: 126135-40-8(Hazardous Substances Data)

Upstream product

• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 
• 30913-86-1 4-(4-bromo-phenyl)-4-oxo-butyric acid methyl ester 
• 1122-91-4 4-bromo-benzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 108-86-1 bromobenzene 

Downstream Products

• 128994-29-6 (S)-(-)-γ-(p-Bromophenyl)-γ-butyrolactone 
• 126135-43-1 (R)-(+)-γ-(p-Bromophenyl)-γ-butyrolactone 

Relevant articles and documents

A substrate-binding metal-organic layer selectively catalyzes photoredox ene-carbonyl reductive coupling reactions

Intermolecular photoredox ene-carbonyl reductive coupling reactions typically have low product selectivity owing to competing dimerization and/or reduction of ketyl radicals. Herein, we report a metal-organic layer (MOL), Hf-Ir-OTf, as a bifunctional photocatalyst for selective photoredox reductive coupling of ketones or aldehydes with electron-deficient alkenes. Composed of iridium-based photosensitizers (Ir-PSs) and triflated Hf12 clusters, Hf-Ir-OTf uses Lewis acidic Hf sites to bind and activate electron-deficient alkenes to accept ketyl radicals generated by adjacent Ir-PSs, thereby suppressing undesired dimerization and reduction of ketyl radicals to enhance the selectivity for the cross-coupling products. The MOL-catalyzed reductive coupling reaction accommodates a variety of olefinic substrates and tolerates reducible groups, nicely complementing current methods for cross-coupling reactions.

Asymmetric synthesis of di- and trisubstituted cyclopropanes through an intramolecular ring closure

An asymmetric synthesis of di- and trisubstituted cyclopropanes proceeding through an intramolecular ring closure of activated chiral benzyl alcohols has been developed. The chiral alcohol intermediates are obtained from asymmetric reduction of readily av

Process for the stereoselective reduction of derivatives of 4-aryl-4-oxobutyric acid

A method for the stereoselective production of 4-aryl-4-hydroxybutanoic acid derivatives involves reduction of the corresponding 4-keto-acid derivative with formic acid and/or formates in presence of a ruthenium-containing catalyst and amine(s). A method