1261360-01-3Relevant academic research and scientific papers
Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues
Florence, Gordon J.,Morris, Joanne C.,Murray, Ross G.,Vanga, Raghava R.,Osler, Jonathan D.,Smith, Terry K.
, p. 8309 - 8320 (2013/07/27)
A highly stereocontrolled synthesis of (+)-chamuvarinin has been completed in 1.5 % overall yield over 20 steps. The key fragment coupling reactions were the addition of alkyne 8 to aldehyde 7 (under Felkin-Anh control), followed by the two step activatio
Synthesis and stereochemical assignment of (+)-chamuvarinin
Florence, Gordon J.,Morris, Joanne C.,Murray, Ross G.,Osler, Jonathan D.,Reddy, Vanga R.,Smith, Terry K.
, p. 514 - 517 (2011/04/17)
A stereocontrolled total synthesis of (+)-chamuvarinin, isolated from the root extract of Uvaria Chamae, utilizes a convergent modular strategy to construct the adjacently linked C15-C28 ether array, followed by a late-stage Julia-Kocienski olefination to
