126145-48-0Relevant academic research and scientific papers
Fused Imidazoles: I. Synthesis of 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole Derivatives
Kavina,Sizov,Yakovlev
, p. 901 - 911 (2018/07/31)
Dehydration of substituted 2-(2-oxopyrrolidin-1-yl)acetamides with phosphoryl chloride provides a convenient method of synthesis of 2-chloro-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles. The latter can be readily converted to various derivatives via introduction and modification of a substituent in the 3-position. The chlorine atom in the 2-position can be removed by hydrogenation over Raney nickel.
