126156-20-5Relevant academic research and scientific papers
Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction
Zhang, Ying,Shen, Hong-Cheng,Li, Yang-Yang,Huang, Yong-Shuang,Han, Zhi-Yong,Wu, Xiang
supporting information, p. 3769 - 3772 (2019/04/01)
A palladium-catalyzed enantioselective coupling of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles is described. The reaction proceeded via a tandem asymmetric Heck insertion and Tsuji-Trost allylation, enabling the rapi
Cu-Catalyzed Enantioselective Ring Opening of Cyclic Diaryliodoniums toward the Synthesis of Chiral Diarylmethanes
Li, Bin,Chao, Zengyin,Li, Chunyu,Gu, Zhenhua
supporting information, p. 9400 - 9403 (2018/07/30)
A Cu-catalyzed enantioselective desymmetrizing ring-opening reaction of six-membered cyclic diaryliodonium salts with carboxylic acids or thioacids is reported for the facile access to chiral diarylmethanes. A Cu/[cyclopropyl bis(oxazoline)] catalyst well
Phosphine/palladium-catalyzed syntheses of alkylidene phthalans, 3-deoxyisoochracinic acid, isoochracinic acid, and isoochracinol
Fan, Yi Chiao,Kwon, Ohyun
supporting information; experimental part, p. 3264 - 3267 (2012/08/28)
In this study we used sequential catalysis-PPh3-catalyzed nucleophilic addition followed by Pd(0)-catalyzed Heck cyclization-to construct complex functionalized alkylidene phthalans rapidly, in high yields, and with good stereoselectivities (E/Z ratios of up to 1:22). The scope of this Michael-Heck reaction includes substrates bearing various substituents around the alkylidene phthalan backbone. Applying this efficient sequential catalysis, we accomplished concise total syntheses of 3-deoxyisoochacinic acid, isoochracinic acid, and isoochracinol.
Synthesis of 4-Alkyl-2-iodosobenzoic Acids: Potent Catalysts for the Hydrolysis of Phosphorous Esters
Panetta, Charles A.,Garlick, Stephanie M.,Durst, H. Dupont,Longo, Frederick R.,Ward, J. Richard
, p. 5202 - 5205 (2007/10/02)
The syntheses of five new 4-alkyl-2-iodosobenzoic acids (3) are described.The iodine atom was introduced by ortho-directed lithiation of 4-alkylbenzyl alcohols followed by treatment with I2.The catalytic effectiveness of each of the products in the hydrolysis of 4-nitrophenyl diphenyl phosphate in microemulsions was studied.The 4-methyl- and 4-ethyl-substituted products were each found to be significantly better catalysts than the standard nonalkylated 2-iodosobenzoic acid (3, R=H).These results would indicate that microemulsions of these materials may find use in detoxification procedures.
