126177-68-2Relevant academic research and scientific papers
Synthesis and immunomodulating activity of 1-amino-2-thiohydantoin derivatives
Blanc,Cussac,Boucherle,Leclerc
, p. 839 - 843 (2007/10/02)
1-Amino-2-thiohydantoin derivatives have been synthesized. Immunomodulating and anticancer activities have been studied. Their activity on the immune system is complex, being either immunodepressive or immunostimulatory according to the doses, or mainly immunostimulatory. These compounds were devoid of any anticancer activity.
Novel Ring-Opening Reactions of 3-Substituted 1-Amino-2-thioxo-4-imidazolidinones: Preparation of Functionalized 3,6-Dihydro-2H-1,3,4-thiadiazines and 3,4-Dihydro-1H-1,2,4-triazoles
Molina, Pedro,Arques, Antonio,Cartagena, Inmaculada,Olmos, Jose Maria
, p. 518 - 522 (2007/10/02)
1-Amino-2-thioxo-4-imidazolidinones 1 react with phenacyl bromides to yield 3-alkoxycarbonylmethyl-5-aryl-2-iminio-3,6-dihydro-2H-1,3,4-thiadiazine salts 3.Compounds 1 also react with aryl isothiocyanates to give N-aryl-N'-(3-aryl/alkyl-4-oxo-2-thioxoimid
