126178-28-7

Upstream product

• 20781-20-8 2,4-Dimethoxybenzylamine 
• 100-52-7 benzaldehyde 

Downstream Products

• 97934-88-8 cis-1-(2,4-dimethoxybenzyl)-3-(α-methyl-β-methoxycarbonylvinylamino)-4-phenyl-2-azetidinone 
• 126178-17-4 2-(2,4-Dimethoxy-benzyl)-1,1-dioxo-3-phenyl-1λ⁶-[1,2]thiazetidine-4-carboxylic acid methyl ester 
• 1235889-65-2 (2R,5R)-dimethyl 1-(2,4-dimethoxybenzyl)-5-(4-methoxyphenyl)-2-phenylpyrrolidine-3,3-dicarboxylate 

Relevant academic research and scientific papers

Dynamic kinetic asymmetric synthesis of substituted pyrrolidines from racemic cyclopropanes and aldimines: Reaction development and mechanistic insights

An enantioselective preparation of 2,5-cis-disubstituted pyrrolidines has been achieved via a dynamic kinetic asymmetric transformation (DyKAT) of racemic donor-acceptor cyclopropanes and (E)-aldimines. Mechanistic studies suggest that isomerization of the aldimine or resultant iminium to the Z geometry is not a pathway that furnishes the observed 2,5-cis-disubstituted products.

2-OXO-1-AZETIDINESULFONIC ACID SALTS

Antibacterial activity is exhibited by beta-lactams having a sulfonic acid salt substituent in the 1-position and an amino or acylamino substituent in the 3-position.