1261796-01-3Relevant academic research and scientific papers
One-pot transition-metal-free synthesis of dibenzo[b,f]oxepins from 2-halobenzaldehydes
Choi, Young Lok,Lim, Hye Sun,Lim, Hwan Jung,Heo, Jung-Nyoung
, p. 5102 - 5105,4 (2012/12/12)
A one-pot transition-metal-free, base-mediated synthesis of dibenzo[b,f]oxepins was developed. The reaction of 2-halobenzaldehydes with (2-hydroxyphenyl)acetonitriles proceeds via a sequential aldol condensation and intramolecular ether formation reaction in the presence of Cs2CO 3 and molecular sieves in toluene.
