1261850-57-0

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 64085-52-5 5-bromo-2-iodo-aniline 
• 21740-00-1 5-bromo-2-iodo-benzoic acid 
• 88-67-5 2-Iodobenzoic acid 
• 293738-03-1 5-bromo-2-iodobenzoyl chloride 

Downstream Products

• 1315267-72-1 methyl 4-[(2-(benzyloxycarbonylamino)-4-bromophenyl)ethynyl]benzoate 
• 1315267-73-2 benzyl 5-bromo-2-[(4-fluorophenyl)ethynyl]phenylcarbamate 
• 1315267-74-3 benzyl 5-bromo-2-[(4-methylphenyl)ethynyl]phenylcarbamate 
• 1315267-75-4 benzyl 5-bromo-2-[(3-methylphenyl)ethynyl]phenylcarbamate 
• 1315267-76-5 benzyl 5-bromo-2-[(2-methylphenyl)ethynyl]phenylcarbamate 
• 1315267-77-6 benzyl 5-bromo-2-[(4-methoxyphenyl)ethynyl]phenylcarbamate 
• 1315267-78-7 benzyl 5-bromo-2-[(3-methoxyphenyl)ethynyl]phenylcarbamate 
• 1315267-79-8 benzyl 5-bromo-2-[(2-methoxyphenyl)ethynyl]phenylcarbamate 
• 1315267-80-1 benzyl 5-bromo-2-[(4-(dimethylamino)phenyl)ethynyl]phenylcarbamate 
• 1315267-81-2 6-bromo-2-(4-cyanophenyl)-1H-indole 
• 675820-99-2 6-bromo-2-(4-nitrophenyl)-1H-indole 
• 1315267-82-3 6-bromo-2-(4-acetylphenyl)-1H-indole 
• 1315267-83-4 6-bromo-2-(4-formylphenyl)-1H-indole 
• 1315267-84-5 methyl 4-(6-bromo-1H-indol-2-yl)benzoate 

Relevant academic research and scientific papers

Copper-Catalyzed Trifunctionalization of Alkynes: Rapid Formation of Oxindoles Bearing Geminal Diboronates

A copper-catalyzed trifunctionalization of alkynes that provides rapid access to oxindoles bearing a geminal diboronate side chain, highlighted by the simultaneous formation of one C?C bond and two C?B bonds, is reported. This new reaction features simple

Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor

The synthesis of 6-bromo-2-arylindoles starting from readily available 2-iodobenzoic acid is presented. Regioselective bromination of the latter was followed by Curtius rearrangement and trapping of the isocyanate with benzyl alcohol led to the benzyl carbamate of 2-iodo-5-bromoaniline. Chemoselective Sonogashira coupling of this compound with arylacetylenes followed by TBAF induced 5-endo-dig cyclization gave the desired bromo indoles. The method allows selective introduction of a bromine atom at the indole C-6 position.