64085-52-5

Basic information

• Product Name: 5-BROMO-2-IODOANILINE
• Synonyms: 5-BROMO-2-IODOANILINE;5-Bromo-2-iodobenzenamine;BenzenaMine, 5-broMo-2-iodo-
• CAS NO: 64085-52-5
• Molecular Formula: C₆H₅BrIN
• Molecular Weight: 297.91907
• Product Categories: Anilines, Amides & Amines;Bromine Compounds;Iodine Compounds
• Mol File: 64085-52-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 55 °C(Solv: hexane (110-54-3); ethyl ether (60-29-7))
• Boiling Point: 309.522 °C at 760 mmHg
• Flash Point: 140.994 °C
• Appearance: /
• Density: 2.292 g/cm³
• Storage Temp.: Refrigerated.
• PKA: 1.46±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-IODOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-IODOANILINE(64085-52-5)
• EPA Substance Registry System: 5-BROMO-2-IODOANILINE(64085-52-5)

Safety Data

• Hazardous Substances Data: 64085-52-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-iodoaniline is a chemical compound with the molecular formula C6H5BrIN. It is a halogenated aniline derivative, characterized by the presence of both bromine and iodine atoms on the benzene ring. 5-BROMO-2-IODOANILINE is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and dyes. It is also utilized in the manufacture of certain polymer materials. 5-Bromo-2-iodoaniline is considered to be a hazardous substance and should be handled with care due to its potential health and environmental risks.

Upstream product

• 88-74-4 2-nitro-aniline 
• 875-51-4 4-Bromo-2-nitroaniline 
• 103-88-8 4-bromoacetanilide 
• 881-50-5 N-(4-bromo-2-nitrophenyl)acetamide 
• 112671-42-8 4-bromo-1-iodo-2-nitrobenzene 

Downstream Products

• 305372-56-9 5-bromo-2-phenylbenzo[d]thiazole 
• 41604-22-2 4-bromo-2-amino-1,1'-biphenyl 
• 1616458-78-6 1-azabicyclo[2.2.2]oct-4-yl (4-bromobiphenyl-2-yl)carbamate 
• 1616458-57-1 1-azabicyclo[2.2.2]oct-4-yl [4-(4-{[2-chloro-4-(hydroxymethyl)-5-methoxyphenyl]-amino}-4-oxobutyl)biphenyl-2-yl]carbamate 
• 1616458-56-0 ethyl 4-{[4-(2-{[(1-azabicyclo[2.2.2]oct-4-yloxy)carbonyl]amino}biphenyl-4-yl)butanoyl]amino}-5-chloro-2-methoxybenzoate 

Relevant articles and documents

TEAD INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

BENZODIAZEPINES AS BROMODOMAIN INHIBITORS

The present invention provides novel benzodiazepine derivatives of Formula I or pharmaceutically acceptable derivatives, polymorphs, salts or prodrugs thereof. Said compounds have potential as bromodomain (BRD) inhibitors.

Stereoselective synthesis of spirocyclic oxindoles based on a one-pot Ullmann coupling/Claisen rearrangement and its application to the synthesis of a hexahydropyrrolo[2,3-b]indole alkaloid

An efficient and convenient approach to the synthesis of spirocyclic oxindoles from iodoindoles has been developed. The most striking feature of this approach is that the sequential intramolecular Ullmann coupling and Claisen rearrangement proceeds in a one-pot manner to afford 3-spiro-2-oxindoles in good yield with excellent diastereoselectivity. Application of this one-pot reaction to chiral non-racemic tertiary alcohol substrates resulted in complete chirality transfer to the spirocyclic quaternary carbon. Using this method, asymmetric total synthesis of (-)-debromoflustramine B was accomplished.