126199-66-4Relevant academic research and scientific papers
Improved synthesis of 1-deoxynojirimycin and facile synthesis of its stereoisomers from (S)-pyroglutamic acid derivative
Ikota, Nobuo,Hirano, Jun-Ichi,Gamage, Ranjith,Nakagawa, Hidehiko,Hama-Inaba, Hiroko
, p. 637 - 643 (2007/10/03)
Improved synthesis of 1-dcoxynojirimycin (9) from (E)-aα,β-unsaturated ester (1) and facile synthesis of 1-deoxyazasugars (14 and 15) from 10 where both substrates (1 and 10) prepared from (S)-pyroglutamic acid were described.
SYNTHESIS OF (2R,3R,4R,5R)-3,4-DIHYDROXY-2,5-DIHYDROXYMETHYLPYRROLIDINE AND (-)-ANISOMYCIN DERIVATIVE FROM (S)-PYROGLUTAMIC ACID DERIVATIVE
Ikota, Nobuo
, p. 983 - 994 (2007/10/02)
Double asymmetric dihydroxylation of (E)-α,β-unsaturated ester (2) with a catalitic amount of potassium osmate and chiral ligand gave dihydroxy compounds (3a and 4a) selectively.Polyhydroxylated pyrrolidines (10 and 14) were synthesized from corresponding methoxymethyl ether (3c) and tert-butyl-dimethylsilyl ether (4d), respectively.
