1262014-09-4Relevant academic research and scientific papers
Synthesis, characterization, DNA binding and cleavage studies of Ru(II) complexes containing oxime ligands
Chitrapriya, Nataraj,Mahalingam, Viswanathan,Zeller, Matthias,Lee, Hyosun,Natarajan, Karuppannan
, p. 30 - 38 (2010)
The Ru(II) precursors, [RuHCl(CO)(EPh3)3] (E = P or As) when reacted with some well known monoxime and dioxime ligands in ethanolic solution afforded the new complexes of the types [RuCl(CO)(EPh3) 2L1], [RuH(CO)(EPh3)2L2] and [RuCl(CO)(EPh 3)2L3] ((H1L1) = diacetylmonoxime, (H 1L2) = dimethylglyoxime and (H2L3) = benzoiloxime). The ligands coordinated in a bidentate chelate mode forming a five membered chelate ring. The molecular structures of two of the complexes have been determined by single crystal X-ray diffraction study. The structural determination confirms the deprotonation of the oxime function. Examination of all the complexes by cyclic voltammetry showed the occurrence of some quasi-reversible redox reactions owing to changes in the oxidation state of the central metal atoms. Structural assignments are supported by combination of IR, UV-Vis, 1H NMR and elemental analyses. In addition, the DNA binding properties and cleavage efficiency of new complexes have been tested.
