1262097-64-2Relevant academic research and scientific papers
Solvent-dependent enantiodivergent mannich-type reaction: Utilizing a conformationally flexible guanidine/bisthiourea organocatalyst
Sohtome, Yoshihiro,Tanaka, Shinji,Takada, Keisuke,Yamaguchi, Takahisa,Nagasawa, Kazuo
supporting information; experimental part, p. 9254 - 9257 (2011/02/22)
Flex control: Malonate and tert-butoxycarbonyl (Boc)-protected imines react in the presence of the flexible catalyst 1 to furnish the S or the R adduct depending upon the solvent used. Kinetic analyses in this enantiodivergent organocatalysis show that en
Asymmetric Mannich-type reaction of aromatic α-amido sulfone with malonate using guanidine-thiourea bifunctional organocatalyst
Takada, Keisuke,Tanaka, Shinji,Nagasawa, Kazuo
experimental part, p. 1643 - 1646 (2009/12/03)
Asymmetric Mannich-type reaction of aromatic α-amido sulfone with malonate, catalyzed by a guanidine-thiourea bifunctional organocatalyst, affords β-amino acid derivatives in high yield with good to excellent enantioselectivity. Georg Thieme Verlag Stuttg
