126222-99-9Relevant academic research and scientific papers
ORALLY ACTIVE RENIN INHIBITORS
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, (2008/06/13)
This invention relates to compounds of the formula STR1 wherein Q, Z, D, E, R 3, R 4, R 5 and R 6 are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.
AMINO ACID DERIVATIVES
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, (2008/06/13)
The compounds of the formula STR1 wherein A, R 1, R. sup.2, R. sup.3, R 4, R 5 and R 6 are as set forth above, are described. The compounds of formula I have an inhibitory activity on the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations for the control or prevention of high blood pressure and cardiac insufficiency.
Orally active renin inhibitors
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, (2008/06/13)
This invention relates to compounds of the formula wherein Q, Z, D, E, R3, R?, R? and R? are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.
