1262235-41-5Relevant academic research and scientific papers
Preparation and evaluation of antibacterial activity of some new 1,2,4-triazole derivatives
Arafa
, p. 1109 - 1115 (2010)
(Chemical Equation Presented) Cyclizations of 1,5-diphenyl[1,2,4]triazole- 3-carbohydrazide 1 and the thiosemicarbazide 2 (derived from 1 by addition to phenylisothiocyanate) under various conditions afforded novel biheterocyclic systems. The newly prepar
Convenient one pot synthesis and antibacterial evaluation of some new Mannich bases carrying 1,2,4-triazolyl moiety
Arafa, Wael A.A.,Mohamed, Asmaa S.
, p. 1661 - 1668 (2011)
A series of Mannich bases were synthesized by a three-component Mannich reaction. The newly synthesized compounds were well characterized by elemental analyses, IR, NMR and mass spectroscopic studies. The potential antibacterial effects of the synthesized compounds were investigated using standard bacterial strains: Gram-positive and Gram-negative bacteria. Interestingly, all the synthesized compounds were observed to be promising leads, possessing moderate to significant inhibitory activity as compared to standard.
