126225-53-4Relevant academic research and scientific papers
Antipicornavirus Activity of Tetrazole Analogues Related to Disoxaril
Diana, Guy D.,Cutcliffe, David,Volkots, Deborah L.,Mallamo, John P.,Bailey, Thomas R.,et al.
, p. 3240 - 3250 (2007/10/02)
A series of tetrazole analogues of Win 54954, a broad-spectrum antipicornavirus compound, has been synthesized to address the acid lability of the oxazoline ring of this series of compounds.The results of X-ray crystallography studies of several members o
Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents
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, (2008/06/13)
Compounds of the formula STR1 wherein: Y is an alkylene bridge of 3-9 carbon atoms; Z is N or HC; R is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when Z is N, R is lower-alkyl; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and Het is selected from specified heterocyclic groups, are useful and antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
