1262319-89-0

Basic information

• Product Name: 3-(m-tolyl)benzo[e][1,2,4]triazine
• Synonyms: 3-(m-tolyl)benzo[e][1,2,4]triazine
• CAS NO: 1262319-89-0
• Molecular Weight: 221.261
• Mol File: 1262319-89-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(m-tolyl)benzo[e][1,2,4]triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(m-tolyl)benzo[e][1,2,4]triazine(1262319-89-0)
• EPA Substance Registry System: 3-(m-tolyl)benzo[e][1,2,4]triazine(1262319-89-0)

Safety Data

• Hazardous Substances Data: 1262319-89-0(Hazardous Substances Data)

Upstream product

• 934367-07-4 (Z)-N′-hydroxy-3-methoxybenzimidamide 
• 614-00-6 N-methyl-N-nitrosoaniline 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 1527-89-5 3-methoxybenzonitrile 
• 1262319-73-2 C₂₀H₁₆N₆ 
• 13050-47-0 3-methylbenzoyl hydrazine 
• 615-43-0 2-iodophenylamine 
• 1262319-55-0 C₂₀H₁₆N₆ 

Downstream Products

• 1450630-91-7 C₁₆H₁₃N₃O₂ 

Relevant articles and documents

Palladium-Catalyzed ortho -Monoacylation of Arenes with Aldehydes via 1,2,4-Benzotriazine-Directed C-H Bond Activation

An efficient palladium-catalyzed C-H bond functionalization/ ortho -monoacylation reaction of 3-aryl-1,2,4-benzotriazines with (hetero)aryl or alkyl aldehydes has been developed, which offers a facile and alternative strategy for direct modification and further diversification of 3-aryl-1,2,4-benzotriazines. Bioactive 1,2,4-benzotriazine has been employed as a novel directing group for the palladium-catalyzed regioselective monoacylation of sp 2 C-H bond protocol with broad substrate scope and good functional group tolerance.

Cobalt-Catalyzed, Directed Intermolecular C-H Bond Functionalization for Multiheteroatom Heterocycle Synthesis: The Case of Benzotriazine

Transition-metal-catalyzed, directed intermolecular C-H bond functionalization is synthetically useful but heavily underexplored in multiheteroatom heterocycle synthesis. Herein we report a cobalt catalytic method for the formation of a three-nitrogen-bearing benzotriazine scaffold via the coupling of arylhydrazine and oxadiazolone. This synthetic protocol features a low-cost base metal catalyst, a maximum number of heteroatoms built into a heterocycle, a distinct synthetic logic for benzotriazines, a superior step economy, and a broad substrate scope.

Reactivity of AllylSmBr/HMPA: Facile Synthesis of 3-Aryl-1,2,4- benzotriazines

3-Aryl-1,2,4-benzotriazines were conveniently prepared in moderate to good yields from 1,l-bis(benzotriazol-1-yl)methylarenes with allylsamarium bromide/hexamethylphosphramide (allylSmBr/HMPA). Preliminary results indicate that HMPA may enhance the reduci

Copper-catalyzed domino reaction of 2-haloanilines with hydrazides: A new route for the synthesis of benzo[e][1,2,4]triazine derivatives

A copper-catalyzed domino reaction for the synthesis of benzo[e][1,2,4]triazine derivatives has been developed using readily available substituted 2-haloanilines and hydrazides as the starting materials. The procedure of the present method is mild, facile

Construction of 3-aryl-1,2,4-benzotriazines via unprecedented rearrangement of bis(benzotriazol-1-yl)methylarenes

3-Aryl-1,2,4-benzotriazines were formed unexpectedly by the treatment of 1,l-bis(benzotriazol-1-yl)methylarenes with allylsamarium bromide. A radical pathway was proposed involving steps, such as fragmentation, ring-opening, and cyclization.