1262395-17-4

Basic information

• Product Name: (1R)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide
• CAS NO: 1262395-17-4
• Molecular Weight: 355.48
• Mol File: 1262395-17-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide(1262395-17-4)
• EPA Substance Registry System: (1R)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide(1262395-17-4)

Safety Data

• Hazardous Substances Data: 1262395-17-4(Hazardous Substances Data)

Upstream product

• 1262396-54-2 2-(1-tert-butoxycarbonyl-piperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid 
• 1262394-87-5 tert-butyl-4-(4-carbamoyl-1-methyl-3-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-1-carboxylate 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 
• 1154100-76-1 4-(1-furan-2-yl-ethylamino)-piperidine-1-carboxylic acid tert-butyl ester 
• 27948-38-5 (1S)-1-(furan-2-yl)ethanamine 
• 16771-84-9 1-cyclohexyl-4-piperidinone 
• 1262396-56-4 1-cyclohexyl-N-[(1S)-1-(furan-2-yl)ethyl]piperidin-4-amine 
• 1262395-10-7 (±)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide 
• 1262396-64-4 1-methyl-3-oxo-2-(piperidin-4-yl)-2,3-dihydro-1H-isoindole-4-carboxamide 
• 108-94-1 cyclohexanone 

Relevant articles and documents

Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515

Poly(ADP-ribose) polymerase-1 (PARP-1) is an enzyme involved in signaling and repair of DNA single strand breaks. PARP-1 employs NAD+ to modify substrate proteins via the attachment of poly(ADP-ribose) chains. PARP-1 is a well established targe