16771-84-9

Usage

Uses

Used in Pharmaceutical Industry:
1-Cyclohexyl-4-piperidinone is used as a building block for the synthesis of antihistamines, analgesics, and antipsychotic drugs. Its unique structure allows for the creation of a diverse range of medicinal compounds, contributing to the development of new treatments for various health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Cyclohexyl-4-piperidinone serves as a crucial intermediate in the production of various agrochemicals. Its incorporation into these products enhances their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Organic Chemistry:
As a versatile intermediate in organic chemistry, 1-Cyclohexyl-4-piperidinone is used for the synthesis of other heterocyclic compounds. Its ability to form a variety of chemical bonds and participate in different reactions makes it an essential component in the creation of complex organic molecules.
Used in Chemical Industry:
1-Cyclohexyl-4-piperidinone's wide range of applications in the chemical industry stems from its compatibility with various chemical processes and its potential to be modified or combined with other compounds. This adaptability positions it as a valuable precursor in the synthesis of a broad spectrum of chemical products.

InChI:InChI=1/C11H19NO/c13-11-6-8-12(9-7-11)10-4-2-1-3-5-10/h10H,1-9H2

Upstream product

• 3592-25-4 1,5-dichloropentan-3-one 
• 108-91-8 cyclohexylamine 
• 1225486-33-8 C₁₃H₂₁NO₃ 
• 73812-87-0 methyl 3-[cyclohexyl-(2-methoxycarbonyl-ethyl)amino]-propionate 

Downstream Products

• 1262396-56-4 1-cyclohexyl-N-[(1S)-1-(furan-2-yl)ethyl]piperidin-4-amine 
• 1262395-13-0 NMS-P₅₁₅ 
• 1262395-17-4 (1R)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide 
• 1262396-58-6 (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid 
• 309722-37-0 (1-cyclohexyl-piperidin-4-yl)-[4-(4-methoxy-phenylsulfanyl)-phenyl]-acetonitrile 
• 147328-60-7 1-Cyclohexyl-4-<(4-cyano-1-naphthyl)methylene>piperidine 
• 100049-66-9 1-cyclohexyl-piperidin-4-ol 

Relevant academic research and scientific papers

Novel symmetrical trans-bis-Schiff bases of N-substituted-4- piperidones: Synthesis, characterization, and preliminary antileukemia activity mensurations

A series of novel symmetrical trans-bis-Schiff bases (11a, 11b, 11c, 11d, 11e, 11f, 11g, 11h, 11i, 11j, 11k, 11l, 11m) were designed and prepared as novel anticancer analogues, with the trans-configuration confirmed by X-ray diffraction. Preliminary inhibitory effects of these compounds on CML K562 cell growth were investigated, and the potential analogue 11e showed an excellent anti-leukemia activity (IC50=6.35 μg/mL), which is higher than that of the clinical drug 5-fluorouracil (IC50=8.48 μg/mL). Complete assignments had been achieved for the title compounds by spectroscopic techniques, and their structure-activity relationships have been studied.

Stepwise versus direct long-range charge separation in molecular triads

Trifunctional electron donor - donor - acceptor molecules are described in which photoinduced charge separation, D2 - D1 - A* → D2 - D1+ - A- , is followed by a charge migration step D

Synthesis and exploratory photophysical investigation of donor-bridge-acceptor systems derived from N-substituted 4-piperidones

We report a two-step synthesis for N-aryl- and N-alkyl-substituted 4-piperidones, in which the N substituent can easily be varied.A number of intramolecular donor-acceptor systems was synthesized from these piperidones by conversion of the carbonyl functionality.The influence of the N-aryl donor on the electronic absorption and fluorescence spectra was investigated systematically.It was concluded that some systems can be used as efficient fluorescent probes with a high sensitivity for solvent polarity.