1262399-93-8Relevant articles and documents
20-HETE FORMATION INHIBITORS
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Paragraph 0257-0260; 0287; 0288, (2020/08/23)
This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.
GPR119 Agonists
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Page/Page column 10-11, (2011/02/18)
GPR119 agonist compounds of the formula: and pharmaceutical compositions for the treatment of diabetes and obesity.