1262415-81-5

Basic information

• Product Name: 2-ethyl-2,3-dihydro-1H-Indene-2-carboxaldehyde
• Synonyms: 2-ethyl-2,3-dihydro-1H-Indene-2-carboxaldehyde
• CAS NO: 1262415-81-5
• Molecular Formula: C12H14O
• Molecular Weight: 174.23896
• Mol File: 1262415-81-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 267.1±29.0 °C(Predicted)
• Appearance: /
• Density: 1.081±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-ethyl-2,3-dihydro-1H-Indene-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-2,3-dihydro-1H-Indene-2-carboxaldehyde(1262415-81-5)
• EPA Substance Registry System: 2-ethyl-2,3-dihydro-1H-Indene-2-carboxaldehyde(1262415-81-5)

Safety Data

• Hazardous Substances Data: 1262415-81-5(Hazardous Substances Data)

Upstream product

• 96-17-3 2-Methylbutyraldehyde 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 109-85-3 2-methoxyethylamine 

Relevant articles and documents

Intramolecular palladium(II)/(IV) catalysed C(sp3)-H arylation of tertiary aldehydes using a transient imine directing group

Palladium catalysed β-C(sp3)-H activation of tertiary aldehydes using a transient imine directing group enables intramolecular arylation to form substituted indane-aldehydes. A simple amine bearing a methyl ether (2-methoxyethan-1-amine) is the optimal TDG to promote C-H activation and reaction with an unactivated proximal C-Br bond. Substituent effects are studied in the preparation of various derivatives. Preliminary mechanistic studies identify a reversible C-H activation, product inhibition and suggest that oxidative addition is the turnover limiting step.