126245-60-1Relevant academic research and scientific papers
Palladium-Catalyzed meta-C-H Olefination of Arene-Tethered Diols Directed by Well-Designed Pyrimidine-Based Group
Fang, Siqiang,Wang, Xiaobing,Yin, Fucheng,Cai, Pei,Yang, Huali,Kong, Lingyi
supporting information, (2019/03/19)
The palladium-catalyzed meta-olefination of arene-tethered diols attached to a well-designed pyrimidine moiety is presented. Applications of the protocol are illustrated by the synthesis of various diol-based natural products, such as coumarins, phenylpropanoids, stilbenes, and chalcones. Advantages of this method are demonstrated through the easy removal of the template and a gram-scale olefination reaction. Finally, experimental verification, including 1H NMR, ESI-MS and IR, and DFT studies are undertaken to elucidate the mechanistic complexity.
Umpolung of Reactivity of Allylsilane, Allylgermane, and Allylstannane: Allylation of Aromatic Compounds with Allylmetal and Allylthallium Bis(trifluoroacetate)
Ochiai, Masahito,Fujita, Eiichi,Arimoto, Masao,Yamaguchi, Hideo
, p. 3994 - 3999 (2007/10/02)
A direct allylation of aromatic compounds using allylsilane, allylgermane, or allylstannane (1) and arylthallium bis(trifluoroacetate) has been developed.The actual transmetalation reagent for 1 in the reaction was proposed to be thallium (III) trifluoroacetate (2), which was proposed together with diarylthallium trifluoroacetate by the disproportionation of arylthallium bis(trifluoroacetate).Keywords-allylation of aromatic compound; allylsilane; allylgermane; allylstannane; arylthallium bis(trifluoroacetate)
