1262536-74-2Relevant academic research and scientific papers
Isoform selective PLD inhibition by novel, chiral 2,8-diazaspiro[4.5]decan-1-one derivatives
Waterson, Alex G.,Scott, Sarah A.,Kett, Nathan R.,Blobaum, Anna L.,Alex Brown,Lindsley, Craig W.
, p. 3670 - 3673 (2018)
This letter describes the on-going SAR efforts to develop PLD1, PLD2 and dual PLD1/2 inhibitors with improved physiochemical and disposition properties as well as securing intellectual property position. Previous PLD inhibitors, based on a triazaspiro[4.5
