1262537-63-2Relevant academic research and scientific papers
Direct and efficient N-heterocyclic carbene-catalyzed hydroxymethylation of aldehydes
Kuhl, Nadine,Glorius, Frank
, p. 573 - 575 (2011)
The N-heterocyclic carbene-catalyzed coupling of several aldehydes with paraformaldehyde is reported, directly providing the corresponding valuable hydroxymethyl ketones. Results of first mechanistic experiments for this remarkably selective transformation are also provided.
