126256-29-9Relevant academic research and scientific papers
Synthesis of β-Oxo Esters from Silyl Enol Ethers and Dichlorobis(phenoxy)methane
Mayr, Herbert,Cambanis, Anton,Baeuml, Englbert
, p. 1571 - 1573 (2007/10/02)
Dichlorobis(phenoxy)methane (1) reacts with trimethylsiloxyalkenes in the presence of 1.2 equiv. of TiCl4 to give β-oxo esters in 44-82percent yield.The title compound 1 is thus employed as a PhO2C+ equivalent.
Oxidation of Alkyl Trimethylsilyl Ketene Acetals with Lead(IV)
Rubottom, George M.,Gruber, John M.,Marrero, Roberto,Juve, Henrik D.,Kim, Wan Chong
, p. 4940 - 4944 (2007/10/02)
Alkyl trimethylsilyl ketene acetals generated from either esters or lactones react with lead(IV) acetate (LTA) or lead(IV) benzoate (LTB) to afford useful yields of the corresponding α-carboyloxy esters and α-carboyloxy lactones.Yields of the reaction products are optimized by use of the appropriate solvent (methylene chloride or benzene) during oxidation.Alkyl groups such as methyl, ethyl, and tert-butyl are all compatible with the procedure, and lactones containing five-, six-, and seven-membered rings give good yields of oxidation products.
