1262660-33-2Relevant academic research and scientific papers
A facile one-pot synthesis of 3-imidazolyl 1,2,4-triazoles and 1,2,4-oxa-diazolones
Dias, Alice M.,Cabral, Isabel M.,Vila-Ch?, A. Sofia,Cunha, Daniela P.,Senhor?es, Nádia,Nobre, Sandra M.,Sousa, Cristina E.,Proen?a, M. Fernanda
body text, p. 2792 - 2796 (2010/12/25)
5-(5-Aminoimidazol-4-yl)-1,2,4-triazol-3-ones were obtained under mild experimental conditions from 5-amino-4-(N-ethoxycarbonyl) cyanoformimidoyl imidazoles and hydrazine in a rapid one-pot reaction. When hydroxylamine hydrochloride was used, in the presence of base, the corresponding 1,2,4-oxadiazol-5-ones were isolated. An equally fast reaction occurred when 5-amino-4-(N-acetyl/benzoyl) cyanoformimidoyl imidazoles were combined with hydrazine to give 5-(5-aminoimidazol-4-yl)-1,2,4-triazoles.
