1262832-35-8Relevant academic research and scientific papers
Asymmetric Michael reaction between aldehydes and nitroalkanes promoted by pyrrolidine-containing C2-symmetric organocatalysts
Bykova,Kostenko,Kucherenko,Zlotin
, p. 1402 - 1406 (2019)
Bifunctional C2-symmetric organocatalysts derived from chiral 1,2-diaminoethanes and (S)-2-aminomethylpyrrolidine were fi rst used for promoting the asymmetric Michael addition of aliphatic aldehydes to nitroalkenes. The synthesized enantioenri
Practical access to highly enantioenriched quaternary carbon Michael adducts using simple organocatalysts
Nugent, Thomas C.,Shoaib, Mohammad,Shoaib, Amna
supporting information; experimental part, p. 52 - 56 (2011/02/24)
A three component catalyst system entailing an amino acid (O tBu-l-threonine), a hydrogen bond donor (sulfamide), and an amine base (DMAP) allows α-branched aldehyde addition to nitroalkenes in good to high yield and excellent ee. Importantly,
