1262869-95-3

Upstream product

• 501-53-1 benzyl chloroformate 
• 50-00-0 formaldehyd 
• 159723-96-3 N-17-Cbz-3-hydroxymorphinan 

Downstream Products

• 1346516-53-7 (6S,6aS,10aS)-benzyl 12-(benzyloxy)-3,5,6,6a,7,8,9,10-octahydro-2H-6,10a-(epiminoethano)phenanthro[1,2-b][1,4]dioxine-15-carboxylate 
• 1346516-52-6 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-1-bromo-2-(2-hydroxyethoxy)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-51-5 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-1-bromo-2-(2-ethoxy-2-oxoethoxy)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-50-4 (6S,6aS,10aS)-benzyl 12-(benzyloxy)-4-methyl-2,3,4,5,6,6a,7,8,9,10-decahydro-6,10a-(epiminoethano)phenanthro[2,1-b][1,4]oxazine-15-carboxylate 
• 1346516-49-1 (6S,6aS,10aS)-benzyl 4-acetyl-12-(benzyloxy)-2,3,4,5,6,6a,7,8,9,10-decahydro-6,10a-(epiminoethano)phenanthro[2,1-b][1,4]oxazine-15-carboxylate 
• 1346516-48-0 (6S,6aS,10aS)-benzyl 12-(benzyloxy)-2,3,4,5,6,6a,7,8,9,10-decahydro-6,10a-(epiminoethano)phenanthro[2,1-b][1,4]oxazine-15-carboxylate 
• 1346516-47-9 (4bS,8aS,9S)-benzyl 2-(2-aminoethoxy)-3-(benzyloxy)-1-bromo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-46-8 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-1-bromo-2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-45-7 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-1-bromo-2-hydroxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-44-6 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-2-hydroxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1346516-43-5 (4bS,8aS,9S)-benzyl 3-(benzyloxy)-2-formyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate 
• 1262869-97-5 (+)-3-hydroxy-2-(hydroxymethyl)-N-(benzyloxycarbonyl)morphinan 
• 1262869-96-4 ((+)-3-hydroxy-N-(benzyloxycarbonyl)morphinan)-2-carboxylic acid 

Relevant academic research and scientific papers

(+)-3-HYDROXYMORPHINAN DERIVATIVES AS NEUROPROTECTANTS

A novel (+)-3-hydroxymorphinan derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating a neurodegenerative disease, are provided.

(+)-3-HYDROXYMORPHINAN-BASED POLYCYCLE DERIVATIVES AS NEUROPROTECTANTS

A (+)-3-hydroxymorphinan-based polycycle derivative of formula (I) is effective as a neuroprotective agent for neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and ischemic