1262872-82-1Relevant academic research and scientific papers
Discovery of novel seven-membered prostacyclin analogues as potent and selective prostaglandin FP and EP3 Dual Agonists
Sugimoto, Isamu,Kambe, Tohru,Okino, Tomotaka,Obitsu, Tetsuo,Ohta, Nobukazu,Nishiyama, Taihei,Kinoshita, Akihiro,Fujimoto, Taku,Egashira, Hiromu,Yamane, Shinsaku,Shuto, Satoshi,Tani, Kousuke,Maruyama, Toru
supporting information, p. 107 - 112 (2017/12/12)
A novel series of prostaglandin analogues with a seven-membered ring scaffold was designed, synthesized, and evaluated for the functional activation of prostaglandin receptors to identify potent and subtype-selective FP and EP3 dual agonists. Starting fro
BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES
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, (2014/01/07)
Provided is a compound which has strong and sustaining intraocular pressure lowering action and, further, has no fear of side effect on eyes. Since a compound represented by the formula (I): wherein definition of each group is as described in the specific
BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES
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, (2012/05/21)
Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and,
