1262873-14-2Relevant academic research and scientific papers
Discovery of novel seven-membered prostacyclin analogues as potent and selective prostaglandin FP and EP3 Dual Agonists
Sugimoto, Isamu,Kambe, Tohru,Okino, Tomotaka,Obitsu, Tetsuo,Ohta, Nobukazu,Nishiyama, Taihei,Kinoshita, Akihiro,Fujimoto, Taku,Egashira, Hiromu,Yamane, Shinsaku,Shuto, Satoshi,Tani, Kousuke,Maruyama, Toru
, p. 107 - 112 (2017/12/12)
A novel series of prostaglandin analogues with a seven-membered ring scaffold was designed, synthesized, and evaluated for the functional activation of prostaglandin receptors to identify potent and subtype-selective FP and EP3 dual agonists. Starting fro
BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES
-
Paragraph 0317 - 0318; 0319; 0384; 0385, (2014/01/07)
Provided is a compound which has strong and sustaining intraocular pressure lowering action and, further, has no fear of side effect on eyes. Since a compound represented by the formula (I): wherein definition of each group is as described in the specific
BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES
-
Page/Page column 16; 19, (2012/05/21)
Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and,
