1262887-50-2

Upstream product

• 1262887-48-8 C₄₂H₄₅N₃O₁₂ 
• 157896-03-2 6-O-Acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranose 
• 228702-12-3 1,2-O-ethylidene(R,S)-α-D-glucopyranose 
• 228702-11-2 3,4,6-tri-O-acetyl-1,2-O-<(R,S)-ethylidene>-α-D-glucopyranose 
• 133076-40-1 6-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranosyl trichloroacetimidate 
• 55682-48-9 1,6-anhydro-2-azido-3,4-di-O-benzyl-2-deoxy-D-glucopyranose 
• 133076-39-8 1,6-di-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranose 
• 1262887-46-6 C₅₈H₆₃N₃O₁₂Si 
• 40608-06-8 levulinic anhydride 
• 604-69-3 β-D-glucose pentaacetate 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Downstream Products

• 1262887-52-4 6-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-α-D-glucopyranosyl-(1->4)-benzyl (3-O-benzyl-2-O-levulinoyl)-β-D-glucopyranosyluronate-(1->4)-(3-O-acetyl-1,6-anhydro-2-azido)-2-deoxy-β-D-glucopyranose 
• 1262887-53-5 6-O-acetyl-2-azido-2-deoxy-3,4-di-O-benzyl-α-D-glucopyranosyl-(1->4)-O-[benzyl 3-O-benzyl-2-O-levulinoyl-β-D-glucopyranosyluronate]-(1->4)-O-2-azido-2-deoxy-1,3,6-tri-O-acetyl-β-D-glucopyranose 
• 1262887-54-6 6-O-acetyl-2-azido-2-deoxy-3,4-di-O-benzyl-α-D-glucopyranosyl-(1->4)-O-[benzyl 3-O-benzyl-2-O-levulinoyl-β-D-glucopyranosyluronate]-(1->4)-O-2-azido-2-deoxy-3,6-di-O-acetyl-β-D-glucopyranose 

Relevant academic research and scientific papers

PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF

Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions.