1262899-40-0Relevant academic research and scientific papers
Highly Enantioselective Cobalt-Catalyzed (3+2) Cycloadditions of Alkynylidenecyclopropanes
Da Concepción, Eduardo,Fernández, Israel,Mascare?as, José L.,López, Fernando
supporting information, p. 8182 - 8188 (2021/03/16)
Low-valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne-tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems containing five-membered rings in good yields and with excellent enantiomeric ratios. We also present a mechanistic discussion based on experimental and computational data, which support the involvement of CoI/CoIII catalytic cycles.
Olefin-Migrative Cleavage of Cyclopropane Rings through the Nickel-Catalyzed Hydrocyanation of Allenes and Alkenes
Hori, Hiroto,Arai, Shigeru,Nishida, Atsushi
, p. 1170 - 1176 (2017/04/13)
A nickel-catalyzed hydrocyanation triggered by hydronickelation of the carbon-carbon double bonds of allenes followed by cyclopropane cleavage is described. The observed regio- and stereochemistries in the products are strongly influenced by the initial hydronickelation step, and allenyl- and methylenecyclopropanes reacted smoothly to promote the cleavage of cyclopropane. In contrast, this cleavage was not observed with vinylidenecyclopropanes, because the initial hydronickelation does not give a suitable intermediate for cleavage of the cyclopropanes. (Figure presented.).
Rhodium-catalyzed carbonylative [3 + 2 + 1] cycloaddition of alkyne-tethered alkylidenecyclopropanes to phenols in the presence of carbon monoxide
Kim, Seyun,Chung, Young Keun
supporting information, p. 4352 - 4355 (2015/01/09)
A novel Rh-catalyzed carbonylative [3 + 2 + 1] cycloaddition of alkyne-tethered alkylidenecyclopropanes for the facile synthesis of bicyclic phenols in high yields has been developed. The reaction tolerated carbon and heteroatoms in the tether.
Nickel-catalyzed [3+2+2] cycloadditions between alkynylidenecyclopropanes and activated alkenes
Saya, Lucia,Bhargava, Gaurav,Navarro, Miguel A.,Gulias, Moises,Lopez, Fernando,Fernandez, Israel,Castedo, Luis,Mascarenas, Jose L.
supporting information; experimental part, p. 9886 - 9890 (2011/02/24)
Now with nickel: [3C+2C+2C] cycloadditions involving non-activated alkylidenecyclopropanes provide a practical entry to a variety of interesting 6,7-fused bicyclic systems (see scheme; cod=1,5-cyclooctadiene). DFT calculations, combined with experimental
