1262957-82-3

Upstream product

• 97189-80-5 1-(benzyloxy)-3-(oxiran-2-yl)propan-2-ol 
• 20194-18-7 sodium phenyl-methanolate 
• 100-51-6 benzyl alcohol 
• 58931-16-1 1-(benzyloxy)-4-penten-2-ol 
• 60656-87-3 benzyloxyacetoaldehyde 

Downstream Products

• 1262957-85-6 2,4-bis(benzoyloxymethyl)thietane 
• 1262957-89-0 C₁₉H₂₀O₂S 
• 122040-29-3 2-[(1R,2S,5R)-1-((1S,3R)-4-Benzyloxy-1-benzyloxymethyl-3-hydroxy-butoxy)-2-isopropyl-5-methyl-cyclohexyl]-1-phenyl-ethanone 
• 122040-14-6 2-[(1R,2S,5R)-1-((S)-2-(R)-1,4-Dioxa-spiro[4.5]dec-2-yl-1-hydroxymethyl-ethoxy)-2-isopropyl-5-methyl-cyclohexyl]-1-phenyl-ethanone 
• 122040-24-8 (2S,4R,6R,7S,10R)-2,4-Bis-benzyloxymethyl-7-isopropyl-10-methyl-1,5-dioxa-spiro[5.5]undecane 
• 122040-13-5 2-[(1R,2S,5R)-1-((1S,3R)-3,4-Dihydroxy-1-hydroxymethyl-butoxy)-2-isopropyl-5-methyl-cyclohexyl]-1-phenyl-ethanone 
• 122040-33-9 (2S,4R)-1,5-Bis-benzyloxy-4-methoxymethoxy-pentan-2-ol 
• 122040-19-1 C₂₅H₄₀O₄Si₂ 

Relevant academic research and scientific papers

Synthesis of thietane nucleoside with an anomeric hydroxymethyl group

Thietane nucleoside 5 with an anomeric hydroxymethyl group was synthesized via the Pummerer reaction. The stereochemistry of the sulfoxide and the nature of the protecting group had no significant effect on the yield of the reaction. When a hypervalent iodine reagent was used, sulfide 16 with O-benzoyl protecting groups gave the ring-expanded nucleoside 21. Unfortunately, synthesized compound 6 did not exhibit anti-HSV activity. Copyright

ENANTIODIFFERENTIATING FUNCTIONALIZATION OF meso-1,3-DIOLS VIA SPIROACETALS DERIVED FROM l-MENTHONE

Enantiodifferentiating functionalization of meso-1,3-diols is realized by the utilization of titanium tetrachloride-promoted selective ring-cleavage reaction of spiroacetals derived from l-menthone.